Phenotypic Detection Of Antibiotic Resistance And Production Of Extended Spectrum Beta lactamases In E.COLI Isolated From UTI Patients At (HMC)

This study aimed at the isolation of antibiotic resistance and ESBL producing E. coli from urinary tract infection patients visiting HMC hospital Peshawar. Method: A total 200 samples were collected cultured on selective media for bacterial isolation. Two hundred isolates subjected to different morphological biochemical tests identification coli. 121 isolations recovered. These sensitivity testing. Eight antibiotics (Meropenem, Tazocin, Ciprofloxacin, Fosfomycin, Cefotaxime, Augmentin, Ceftazidime, Cefepime) used this purpose. Result: The showed high these such as meropenem having percent 1.85 while is 98.14%, Tazocin 9.25 85.18%, Ciprofloxacin 87.96 percent, 12.03%, Fosfomycin 3.70 95.37%, Cefepime 100 percent. then investigated existence enzymes production through double disc diffusion test. Among isolates, 108 positive production. Conclusion: Current findings highlight prevalence multi drug resistant in clinical samples. Proper management control measures are needed spread highly pathogenic ensure public health safety.